Children who have never achieved 6 months of continuously dry nights.
Causes of Primary Enuresis:
• Nocturnal polyuria:
• Increased urine production while asleep due to
• Decreased bladder capacity
• Detrusor overactivity
• Associated sleep arousal disturbances
• Global maturation delay
• Genetics:
- 75% incidence of NE in children when both parents had a history of NE
- 50% when only one parent had history of NE
- 15% when neither parent had a history of NE
